{"id":1261,"date":"2018-11-14T12:54:21","date_gmt":"2018-11-14T11:54:21","guid":{"rendered":"http:\/\/www.mc-praha.cz\/mcp\/?p=1261"},"modified":"2026-03-25T10:30:28","modified_gmt":"2026-03-25T09:30:28","slug":"projekty-kmenove-bunky","status":"publish","type":"post","link":"https:\/\/www.mc-praha.cz\/mcp\/projekty-kmenove-bunky\/","title":{"rendered":"Kmenov\u00e9 bu\u0148ky"},"content":{"rendered":"

 <\/p>\n

Slibn\u00fdm n\u00e1strojem v modern\u00ed terapii jsou tzv. kmenov\u00e9 bu\u0148ky. Obecn\u011b se jedn\u00e1 <\/strong>o z\u00e1rode\u010dn\u00e9 bu\u0148ky, ze kter\u00fdch se mohou „vyp\u011bstovat“ r\u016fzn\u00e9 tk\u00e1n\u011b a org\u00e1ny <\/strong>(nap\u0159. chrupavka, oko…). <\/strong><\/p>\n

Z\u00e1kladn\u00ed definice t\u011bchto bun\u011bk je z oboru embryologie zn\u00e1m\u00e1 des\u00edtky let. K v\u00fdrazn\u00e9mu posunu v l\u00e9\u010db\u011b do\u0161lo v roce 2006, kdy profesor Yamanaka<\/strong><\/span><\/a> dok\u00e1zal z b\u011b\u017en\u00e9 bu\u0148ky vytvo\u0159it z\u00e1rode\u010dnou bu\u0148ku a tu n\u00e1sledn\u011b p\u0159eprogramovat na jinou tk\u00e1\u0148 (nap\u0159. m\u00edsto ko\u017en\u00ed bu\u0148ky tak vzniklo svalov\u00e9 vl\u00e1kno). N\u00e1sledn\u011b vznikl nov\u00fd sm\u011br v\u00fdzkumu, v n\u011bm\u017e nebylo nutn\u00e9 vych\u00e1zet z lidsk\u00fdch embryon\u00e1ln\u00edch bun\u011bk, jejich\u017e pou\u017eit\u00ed bylo pro mnoh\u00e9 z pochopiteln\u00fdch mor\u00e1ln\u00edch d\u016fvod\u016f nep\u0159ijateln\u00e9. Za\u010dala tak \u00e9ra nov\u00e9ho v\u011bdn\u00edho oboru, v r\u00e1mci kter\u00e9ho vznikla \u0159ada nov\u00fdch terapeutick\u00fdch\u00a0<\/strong><\/span>postup\u016f<\/strong><\/span><\/a>.<\/p>\n

Kmenov\u00fdch bun\u011bk se standardn\u011b vyu\u017e\u00edv\u00e1 v hematologii, v sou\u010dasnosti v\u0161ak p\u0159ib\u00fdv\u00e1 \u0159ada protokol\u016f pro jejich vyu\u017eit\u00ed v imunologii (l\u00e9\u010dba imunodeficit\u016f, autoimunitn\u00edch onemocn\u011bn\u00ed, chronick\u00fdch infekc\u00ed) a u onkologick\u00fdch onemocn\u011bn\u00edch.<\/p>\n

Samostatnou kapitolou v modern\u00ed medic\u00edn\u011b je pak proces regenerace, v n\u011bm\u017e se vyu\u017e\u00edv\u00e1 unik\u00e1tn\u00edch vlastnost\u00ed tzv. mezenchym\u00e1ln\u00edch kmenov\u00fdch bun\u011bk k obnov\u011b po\u0161kozen\u00fdch tk\u00e1n\u00ed.<\/p>\n

Medic\u00ednsk\u00e9 centrum Praha vypracovalo a zavedlo protokoly pro zpracov\u00e1n\u00ed a ulo\u017een\u00ed tzv. hematopoetick\u00fdch kmenov\u00fdch bun\u011bk z pupe\u010dn\u00edkov\u00e9<\/span> krve<\/span><\/strong><\/a> a perifern\u00ed krve\u00a0<\/strong><\/span>dosp\u011bl\u00fdch<\/strong><\/span><\/a>, a tak\u00e9 tk\u00e1n\u011b pupe\u010dn\u00edku, kter\u00e1 je zdrojem tzv. mezenchym\u00e1ln\u00edch kmenov\u00fdch bun\u011bk. Archivace t\u011bchto bun\u011bk m\u00e1 jedine\u010dn\u00fd preventivn\u00ed charakter<\/strong><\/span><\/a>.<\/p>\n

V\u00edce informac\u00ed naleznete na webov\u00fdch str\u00e1nk\u00e1ch\u00a0www.kmenovky.cz<\/a><\/strong><\/p>\n

Dotazy, podn\u011bty, nab\u00edz\u00edme spolupr\u00e1ci nad\u0161en\u00fdm l\u00e9ka\u0159\u016fm i badatel\u016fm.<\/strong>
\nNapi\u0161te n\u00e1m:<\/strong> info@kmenovky.cz<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

  Slibn\u00fdm n\u00e1strojem v modern\u00ed terapii jsou tzv. kmenov\u00e9 bu\u0148ky. Obecn\u011b se jedn\u00e1 o z\u00e1rode\u010dn\u00e9 […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"link","meta":{"_uag_custom_page_level_css":""},"categories":[9],"tags":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"boldthemes_grid":false,"boldthemes_grid_11":false,"boldthemes_grid_22":false,"boldthemes_grid_21":false,"boldthemes_grid_12":false,"boldthemes_latest_posts":false,"boldthemes_grid_gallery":false},"uagb_author_info":{"display_name":"Jbednar","author_link":"https:\/\/www.mc-praha.cz\/mcp\/author\/jbednar\/"},"uagb_comment_info":0,"uagb_excerpt":"  Slibn\u00fdm n\u00e1strojem v modern\u00ed terapii jsou tzv. kmenov\u00e9 bu\u0148ky. Obecn\u011b se jedn\u00e1 o z\u00e1rode\u010dn\u00e9 […]","post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/1261"}],"collection":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/comments?post=1261"}],"version-history":[{"count":17,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/1261\/revisions"}],"predecessor-version":[{"id":4739,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/1261\/revisions\/4739"}],"wp:attachment":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/media?parent=1261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/categories?post=1261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/tags?post=1261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}