Je prok\u00e1z\u00e1no, \u017ee ne v\u0161echny bakterie po\u0161kozuj\u00ed lidsk\u00e9 t\u011blo. Ve skute\u010dnosti mnoho z nich jsou sou\u010d\u00e1st\u00ed b\u011b\u017en\u00e9 lidsk\u00e9 mikrofl\u00f3ry. Z tohoto d\u016fvodu vzniklo relativn\u011b nov\u00e9 pole ve studiu komplexn\u00edch vztah\u016f mezi mikroorganismy a \u010dlov\u011bkem.<\/p>\n
Mikroorganismy v lidsk\u00e9m st\u0159ev\u011b m\u00e1j\u00ed z\u00e1sadn\u00ed funkc\u00ed p\u0159i rozvoji lidsk\u00e9ho imunitn\u00edho syst\u00e9mu t\u00edm, \u017ee n\u00e1s chr\u00e1n\u00ed p\u0159ed onemocn\u011bn\u00edm, produkuj\u00ed vitam\u00edny, jako je vitamin K, B12 atd. Proto je d\u016fle\u017eit\u00e9, aby zdrav\u00fd \u010dlov\u011bk m\u011bl stabiln\u00ed prost\u0159ed\u00ed mikroorganism\u016f.
\nV\u011bdci z Brigham and Women\u2019s Hospital ve spolupr\u00e1ci s d\u011btskou Nemocnic\u00ed ve Spojen\u00fdch st\u00e1tech ned\u00e1vno zve\u0159ejnili studii, ve kter\u00e9 zkoumali fek\u00e1ln\u00ed mikroorganismus 56 kojenc\u016f s alergi\u00ed na potraviny a fek\u00e1ln\u00ed mikroorganismus 98 zdrav\u00fdch kojenc\u016f p\u0159edstavuj\u00edc\u00ed kontroln\u00ed skupinu. Mezi stovkami r\u016fzn\u00fdch mikroorganism\u016f zjistili, \u017ee zdrav\u00e9 d\u00edt\u011b m\u00e1 v\u011bt\u0161\u00ed mno\u017estv\u00ed druh\u016f Clostridiales a Bacteroidales ve srovn\u00e1n\u00ed s d\u00edt\u011btem s potravinov\u00fdmi alergiemi. Prok\u00e1zalo se, \u017ee my\u0161i jsou skute\u010dn\u011b chr\u00e1n\u011bny proti potravinov\u00fdm alergi\u00edm v p\u0159\u00edpad\u011b transplantace stolice zdrav\u00e9ho d\u00edt\u011bte do my\u0161\u00ed s potravinov\u00fdmi alergiemi.<\/p>\n
\u201eNejen\u017ee m\u016f\u017eeme zabr\u00e1nit vzniku potravinov\u00fdch alergi\u00ed, ale v preklinick\u00fdch modelech lze zvr\u00e1tit existuj\u00edc\u00ed potravinov\u00e9 alergie. T\u011bmito mikroby obnovujeme imunitn\u00ed syst\u00e9m, „uvedla Dr. Lynn Bry, MD, PhD.<\/p>\n
P\u0159esto\u017ee studie je st\u00e1le ve f\u00e1zi testov\u00e1n\u00ed na zv\u00ed\u0159atech, jsme nyn\u00ed o krok bl\u00ed\u017ee k pochopen\u00ed komplexn\u00edch interakc\u00ed \u010dlov\u011bka a bakteri\u00ed a o krok bl\u00ed\u017ee k \u00fapln\u00e9 prevenci alergi\u00ed na potraviny. Prozat\u00edm existuje jedna aplikace transplantace stolice v nemocnic\u00edch po cel\u00e9m sv\u011bt\u011b, v\u010detn\u011b \u010cesk\u00e9 republiky.
\nJe to b\u011b\u017en\u011b pou\u017e\u00edvan\u00fd postup zvl\u00e1\u0161\u0165 v boji proti opakuj\u00edc\u00edm se infekc\u00edm Clostridium difficile (druh bakteri\u00ed, kter\u00e9 se b\u011b\u017en\u011b nach\u00e1zej\u00ed v mal\u00e9m mno\u017estv\u00ed ve st\u0159evech). Tato infekce zp\u016fsobuje stav zn\u00e1m\u00fd jako pseudomembran\u00f3zn\u00ed kolitida.
\nPseudomembran\u00f3zn\u00ed kolitida vznik\u00e1 p\u0159i nerovnov\u00e1ze bakteri\u00ed v d\u016fsledku nadm\u011brn\u00e9ho pou\u017e\u00edv\u00e1n\u00ed antibiotik. Kv\u016fli t\u00e9to nerovnov\u00e1ze, Clostridium Difficile se rychle p\u0159emno\u017e\u00ed a zp\u016fsobuje zdravotn\u00ed probl\u00e9my.<\/p>\n
Transplantace stolice podporuje rovnov\u00e1\u017en\u00e9 prost\u0159ed\u00ed ve st\u0159ev\u011b a br\u00e1n\u00ed tak pror\u016fst\u00e1n\u00ed Clostridium Difficile a zp\u016fsobov\u00e1n\u00ed probl\u00e9m\u016f, zejm\u00e9na v p\u0159\u00edpadech, kdy se p\u0159i kontrole t\u00e9to infekce uk\u00e1\u017ee, \u017ee antibiotika jsou zbyte\u010dn\u00e9.
\n—
\nZdroj:
\n1. Abdel-Gadir, A. et. al. (2019, June 24). Microbiota therapy acts via a regulatory T cell MyD88\/ROR\u03b3t pathway to suppress food allergy. https:\/\/www.nature.com\/articles\/s41591-019-0461-z<\/p>\n
2. Brigham and Women\u2019s Hospital. (2019, June 24). Press Release New Therapy Targets Gut Bacteria to Prevent and Reverse Food Allergies. https:\/\/www.brighamandwomens.org\/about-bwh\/newsroom\/press-releases-detail?id=3352<\/p>\n","protected":false},"excerpt":{"rendered":"
Je prok\u00e1z\u00e1no, \u017ee ne v\u0161echny bakterie po\u0161kozuj\u00ed lidsk\u00e9 t\u011blo. Ve skute\u010dnosti mnoho z nich jsou […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"image","meta":{"_uag_custom_page_level_css":""},"categories":[1],"tags":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"boldthemes_grid":false,"boldthemes_grid_11":false,"boldthemes_grid_22":false,"boldthemes_grid_21":false,"boldthemes_grid_12":false,"boldthemes_latest_posts":false,"boldthemes_grid_gallery":false},"uagb_author_info":{"display_name":"Jbednar","author_link":"https:\/\/www.mc-praha.cz\/mcp\/author\/jbednar\/"},"uagb_comment_info":0,"uagb_excerpt":"Je prok\u00e1z\u00e1no, \u017ee ne v\u0161echny bakterie po\u0161kozuj\u00ed lidsk\u00e9 t\u011blo. Ve skute\u010dnosti mnoho z nich jsou […]","post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/3152"}],"collection":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/comments?post=3152"}],"version-history":[{"count":8,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/3152\/revisions"}],"predecessor-version":[{"id":3224,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/posts\/3152\/revisions\/3224"}],"wp:attachment":[{"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/media?parent=3152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/categories?post=3152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mc-praha.cz\/mcp\/wp-json\/wp\/v2\/tags?post=3152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}